human ZYX Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-229020
Availability:
3-5 weeks
Name:
Ad-h-ZYX
This is an Adenovirus expressing Human ZYX.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ZYX
- Gene Name
- zyxin
- Gene ID
- 7791
- Gene Synonyms
- ESP-2; HED-2
- ORF Size
- 1719 bp
- RefSeq#
- BC008743
- Gene Description
- Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.
- UniGene ID
- Hs.490415
- HGNC ID
- HGNC:13200
Related Products
Product | Cat No. |
---|---|
AAV-h-ZYX | AAV-229020 |
AAV-m-ZYX | AAV-277172 |
Ad-m-ZYX | ADV-277172 |
AAV-h-ZYX-shRNA | shAAV-229020 |
AAV-m-ZYX-shRNA | shAAV-277172 |
Ad-h-ZYX-shRNA | shADV-229020 |
Ad-m-ZYX-shRNA | shADV-277172 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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