Adenovirus Control Products
Why do you need a control adenovirus for your studies?
To determine whether the infection efficiency or the biological changes observed is caused by the gene of interest in the recombinant adenovirus used, you need to use a control adenovirus that does not express your GOI/shRNA/gRNA.
Controls for shRNA Adenovirus
For shRNA adenovirus, we highly recommnend using a scramble shRNA adenovirus as the control. shRNA itself may cause non-specific effects in the infected cells, so a non-targeting scrambled shRNA is needed as a control. As with over-expression, if your adenovirus has a fluorescence reporter, then choose the control virus with the same fluorescence reporter.