Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

HPSE2

Gene Name

heparanase 2 (inactive)

Gene ID

60495

Gene Synonyms

HPA2; HPR2; UFS; UFS1

ORF Size

1779 bp

RefSeq#

BC112356

Gene Description

HPSE2 encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.

UniGene ID

Hs.500750

HGNC ID

HGNC:18374