human HPS4 Adenovirus

Name 
Ad-h-HPS4
Cat No 
ADV-211504
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human HPS4.

ADV-211504
Ad-h-HPS4

Ready-to-use Adenovirus expressing Human HPS4 (HPS4, biogenesis of lysosomal organelles complex 3 subunit 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BLOC3S2; Hermansky-Pudlak syndrome 4 protein; LE; light-ear protein homolog
Description (eCommerce)
Hermansky-Pudlak syndrome 4 protein (HPS4) component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in the gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism [taken from NCBI Entrez Gene (Gene ID: 89781)].
Description (Vector)
HPS4 encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.
Gene ID
89781
Gene Name (eCommerce)
HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Gene Name (Vector)
HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
Gene Symbol
HPS4
HGNC ID
HGNC:15844
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2127
ORF Size (bp)
2127 bp
Protein Name (eCommerce)
Hermansky-Pudlak syndrome 4 protein
RefSeq ID
NM_022081
RefSeq Synonyms
NM_152841, NM_022081, BC065030,
Research Areas
Lysosome
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
Hermansky-Pudlak syndrome 4 protein (HPS4) component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in the gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism [taken from NCBI Entrez Gene (Gene ID: 89781)].
UniGene ID
Hs.474436
UniProt ID (eCommerce)
Q9NQG7

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.