human HPS4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-211504
Availability:
4-5 weeks
Name:
AAV-h-HPS4-shRNA
This is an AAV expressing shRNA for silencing of Human HPS4.
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Product Info
- Knockdown
- >60% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- HPS4
- Gene Name
- HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
- Gene ID
- 89781
- Gene Synonyms
- BLOC3S2; LE
- ORF Size
- 2127 bp
- RefSeq#
- NM_022081
- Gene Description
- HPS4 encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.
- UniGene ID
- Hs.474436
- HGNC ID
- HGNC:15844
Related Products
Product | Cat No. |
---|---|
AAV-h-HPS4 | AAV-211504 |
AAV-m-HPS4 | AAV-261640 |
Ad-h-HPS4 | ADV-211504 |
Ad-m-HPS4 | ADV-261640 |
AAV-m-HPS4-shRNA | shAAV-261640 |
Ad-h-HPS4-shRNA | shADV-211504 |
Ad-m-HPS4-shRNA | shADV-261640 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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