human TRAF4 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-226332
Availability:
3-5 weeks
Name:
AAV-h-TRAF4
This is an AAV expressing Human TRAF4.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TRAF4
- Gene Name
- TNF receptor associated factor 4
- Gene ID
- 9618
- Gene Synonyms
- CART1; MLN62; RNF83
- ORF Size
- 1413 bp
- RefSeq#
- BC001769
- Gene Description
- TRAF4 encodes a member of the TNF receptor associated factor (TRAF) family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. The encoded protein has been shown to interact with neurotrophin receptor, p75 (NTR/NTSR1), and negatively regulate NTR induced cell death and NF-kappa B activation. This protein has been found to bind to p47phox, a cytosolic regulatory factor included in a multi-protein complex known as NAD(P)H oxidase. This protein thus, is thought to be involved in the oxidative activation of MAPK8/JNK. Alternatively spliced transcript variants have been observed but the full-length nature of only one has been determined.
- UniGene ID
- Hs.8375
- HGNC ID
- HGNC:12034
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