Interleukin 6 Adenovirus
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. The interleukins are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The functions of different interleukins vary from regulation inflammatory and immune responses, functioning as autocrine factor and regulation and/or inhibition of other interleukins.
1380
Ad-IL6
Ready-to-use Interleukin 6 Adenovirus. Ad-IL6, Interleukin 6 , HGF,HSF,IL6,BSF2,IL-6,IFNB2 adenovirus 1380
Gene Reference Data
Alternate Names
BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Description (Vector)
IL6 encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
Gene ID
3569
Gene Name (Vector)
interleukin 6
Gene Symbol
IL6
HGNC ID
HGNC:6018
ORF Size (aa)
639
RefSeq ID
NM_000600
RefSeq Synonyms
NM_001318095, NM_000600, BC015511,
Species
human
UniGene ID
Hs.654458
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.