human IL6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human IL6.
shADV-212200
Ad-h-IL6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human IL6 (interleukin 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BSF-2; BSF2; CDF; HGF; HSF; IFN-beta-2; IFNB2; IL-6
Description (Vector)
IL6 encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
Gene ID
3569
Gene Name (Vector)
interleukin 6
Gene Symbol
IL6
HGNC ID
HGNC:6018
ORF Size (aa)
639
RefSeq ID
NM_000600
RefSeq Synonyms
NM_001318095, NM_000600, BC015511,
Species
human
UniGene ID
Hs.654458
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.