Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

DOLK

Gene Name

dolichol kinase

Gene ID

22845

Gene Synonyms

CDG1M; DK; DK1; SEC59; TMEM15

ORF Size

1617 bp

RefSeq#

BC035556

Gene Description

DOLK catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.

UniGene ID

Hs.531563

HGNC ID

HGNC:23406