human DOLK shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human DOLK.
shAAV-207253
AAV-h-DOLK-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human DOLK (dolichol kinase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CDG1M; DK; DK1; SEC59; TMEM15
Description (Vector)
DOLK catalyzes the CTP-mediated phosphorylation of dolichol, and is involved in the synthesis of Dol-P-Man, which is an essential glycosyl carrier lipid for C- and O-mannosylation, N- and O-linked glycosylation of proteins, and for the biosynthesis of glycosyl phosphatidylinositol anchors in endoplasmic reticulum. Mutations in this gene are associated with dolichol kinase deficiency.
Gene ID
22845
Gene Name (Vector)
dolichol kinase
Gene Symbol
DOLK
HGNC ID
HGNC:23406
ORF Size (aa)
1617
ORF Size (bp)
1617 bp
RefSeq ID
NM_014908
RefSeq Synonyms
NM_014908, BC035556,
Species
human
UniGene ID
Hs.531563
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.