Cre Recombinase

Product Category: human Adenovirus Type5 (dE1/E3)

Description:

Cre Recombinase is a Type I topoisomerase from bacteriophage P1 that catalyzes the site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cells or experimental animals.

This adenovirus expresses both Cre recombinase and GFP as marker.

Titer: 1x10¹⁰ PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

References:

• Transcription Coactivator Pbp/Med1 Deficient Hepatocytes Are Not Susceptible To Diethylnitrosamine-Induced Hepatocarcinogenesis In The Mouse
  Carcinogenesis. 2010. 31(2):318-25.

• Podocytes require the engagement of cell surface heparan sulfate proteoglycans for adhesion to extracellular matrices
  Kidney International. 2010. XX(XX):XX

Cat. No.	Tag	Promoter		Species	Price **	Availability
1700	GFP	CMV			$445.00	In Stock

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