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Mitogen-activated protein kinase kinase 5 adenovirus


Product Name: Ad-MEK5

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: MEK5

Gene Alias: MEK5, MAP2K5, MAPKK5, PRKMK5, HST17454

GeneBank Number: BC008838

Description:

A family of protein kinases upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr amino acid motif just upstream of a conserved APE amino acid sequence. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. Additional MEK proteins include MEK-3 (alternatively designated MKK-3), which functions to activate the MAP kinase related protein p38 MAP kinase, and MEK-4 (alternatively designated SEK1 or MKK-4), which activates both p38 MAP kinase and JNK. A fifth member of this family, MEK-5, appears to specifically phosphorylate ERK 5, whereas MEK-6 phosphorylates p38 and p38beta. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Titer: 1x1010 PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

Catalog No. Tag Promoter Species Price **
1560 CMV human $690.00

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