human MAP2K5 Over-expression AAV
Category: AAV > Over-Expression
Cat. No: AAV-214920
Availability:
3-5 weeks
Name:
AAV-h-MAP2K5
This is an AAV expressing Human MAP2K5.
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Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- CMV (default), or choose from 30 different ubiquitous or cell specific promoter
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- MAP2K5
- Gene Name
- mitogen-activated protein kinase kinase 5
- Gene ID
- 5607
- Gene Synonyms
- HsT17454; MAPKK5; MEK5; PRKMK5
- ORF Size
- 1347 bp
- RefSeq#
- BC008838
- Gene Description
- MAP2K5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.
- UniGene ID
- Hs.114198
- HGNC ID
- HGNC:6845
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