human TLR9 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-231878
Availability:
6-8 weeks
Name:
AAV-h-TLR9-shRNA
This is an AAV expressing shRNA for silencing of Human TLR9.
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Product Info
- Knockdown
- shRNA screening service available, please inquire about this service or other options.
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- TLR9
- Gene Name
- toll like receptor 9
- Gene ID
- 54106
- Gene Synonyms
- CD289
- ORF Size
- 3099 bp
- RefSeq#
- NM_017442
- Gene Description
- TLR9 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
- UniGene ID
- Hs.87968
- HGNC ID
- HGNC:15633
Related Products
Product | Cat No. |
---|---|
AAV-h-TLR9 | AAV-231878 |
AAV-m-TLR9 | AAV-274288 |
Ad-h-TLR9 | ADV-231878 |
Ad-m-TLR9 | ADV-274288 |
AAV-m-TLR9-shRNA | shAAV-274288 |
Ad-h-TLR9-shRNA | shADV-231878 |
Ad-m-TLR9-shRNA | shADV-274288 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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