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mouse TLR9 shRNA silencing Adenovirus

Name 
Ad-m-TLR9-shRNA
Cat No 
shADV-274288
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Tlr9.

shADV-274288
Ad-m-TLR9-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Tlr9 (toll-like receptor 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
Gene ID
81897
Gene Name (Vector)
toll-like receptor 9
Gene Symbol
Tlr9
ORF Size (aa)
3099
ORF Size (bp)
3099 bp
RefSeq ID
NM_031178
RefSeq Synonyms
NM_031178, BC172644,
Species
mouse
UniGene ID
Mm.44889

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.