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mouse TLR9 Over-expression AAV

Name 
AAV-m-TLR9
Cat No 
AAV-274288
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Mouse Tlr9.

AAV-274288
AAV-m-TLR9

Ready-to-use AAV expressing Mouse Tlr9 (toll-like receptor 9). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Description (Vector)
Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Controls lymphocyte response to Helicobacter infection.
Gene ID
81897
Gene Name (Vector)
toll-like receptor 9
Gene Symbol
Tlr9
ORF Size (aa)
3099
ORF Size (bp)
3099 bp
RefSeq ID
NM_031178
RefSeq Synonyms
NM_031178, BC172644,
Species
mouse
UniGene ID
Mm.44889

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.