Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Ttk

Gene Name

Ttk protein kinase

Gene ID

22137

Gene Synonyms

AL022661; esk; Esk1; Mps1; PYT

ORF Size

2493 bp

RefSeq#

BC058851

Gene Description

Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint.

UniGene ID

Mm.1904