Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Kalrn

Gene Name

kalirin, RhoGEF kinase

Gene ID

545156

Gene Synonyms

2210407G14Rik; AV235988; DUET; E530005C20Rik; Gm539; Hapip; TRAD

ORF Size

4965 bp

RefSeq#

BC172101

Gene Description

Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.

UniGene ID

Mm.450612