Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

WWP2

Gene Name

WW domain containing E3 ubiquitin protein ligase 2

Gene ID

11060

Gene Synonyms

AIP2; WWp2-like

ORF Size

2613 bp

RefSeq#

BC013645

Gene Description

WWP2 encodes a member of the Nedd4 family of E3 ligases, which play an important role in protein ubiquitination. The encoded protein contains four WW domains and may play a role in multiple processes including chondrogenesis and the regulation of oncogenic signaling pathways via interactions with Smad proteins and the tumor suppressor PTEN. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 10.

UniGene ID

Hs.408458

HGNC ID

HGNC:16804