Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TTC8

Gene Name

tetratricopeptide repeat domain 8

Gene ID

123016

Gene Synonyms

BBS8; RP51

ORF Size

1596 bp

RefSeq#

BC026351

Gene Description

TTC8 encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. Alternate transcriptional splice variants have been characterized.

UniGene ID

Hs.303055

HGNC ID

HGNC:20087