Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TBPL1

Gene Name

TATA-box binding protein like 1

Gene ID

9519

Gene Synonyms

MGC:8389; MGC:9620; STUD; TLF; TLP; TRF2

ORF Size

561 bp

RefSeq#

BC017559

Gene Description

TBPL1 encodes a member of the TATA box-binding protein family. TATA box-binding proteins play a critical role in transcription by RNA polymerase II as components of the transcription factor IID (TFIID) complex. The encoded protein does not bind to the TATA box and initiates transcription from TATA-less promoters. TBPL1 plays a critical role in spermatogenesis, and single nucleotide polymorphisms in this gene may be associated with male infertility. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.

UniGene ID

Hs.486507

HGNC ID

HGNC:11589