Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

PHLDA2

Gene Name

pleckstrin homology like domain family A member 2

Gene ID

7262

Gene Synonyms

BRW1C; BWR1C; HLDA2; IPL; TSSC3

ORF Size

459 bp

RefSeq#

BC005034

Gene Description

PHLDA2 is located in a cluster of imprinted genes on chromosome 11p15.5, which is considered to be an important tumor suppressor gene region. Alterations in this region may be associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. PHLDA2 has been shown to be imprinted, with preferential expression from the maternal allele in placenta and liver.

UniGene ID

Hs.154036

HGNC ID

HGNC:12385