human NAMPT Adenovirus
This is an Adenovirus expressing Human NAMPT.
ADV-216295
Ad-h-NAMPT
Ready-to-use Adenovirus expressing Human NAMPT (nicotinamide phosphoribosyltransferase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110035O14Rik; NAmPRTase; Nampt; nicotinamide phosphoribosyltransferase; PBEF; PBEF1; pre-B cell-enhancing factor; pre-B-cell colony-enhancing factor 1; VF; VISFATIN
Description (eCommerce)
PBEF is also known as visfatin and was first identified as a factor that enhanced the differentiation of B-cells. It is a secreted factor that is highly expressed in adipocytes. Intracellularly, PBEF acts as a cytosolic enzyme involved in nicotinamide adenine dinucleotide (NAD) synthesis. PBEF levels positively correlate with obesity and type 2 diabetes mellitus and can bind the insulin receptor to lower blood sugar.
Description (Vector)
NAMPT encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. NAMPT has a pseudogene on chromosome 10.
Gene ID
10135
Gene Name (eCommerce)
nicotinamide phosphoribosyltransferase
Gene Name (Vector)
nicotinamide phosphoribosyltransferase
Gene Symbol
NAMPT
HGNC ID
HGNC:30092
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1476
ORF Size (bp)
1476 bp
Protein Name (eCommerce)
Nicotinamide phosphoribosyltransferase
RefSeq ID
NM_005746
RefSeq Synonyms
NM_005746, BC106046, BC072439,
Research Areas
Insulin Signaling,Metabolism/Metabolic Process,Signal Transduction
Research Areas (Faceted)
cell_biology,metabolism,signal_transduction
Species
human
Target Sentence
PBEF is also known as visfatin and was first identified as a factor that enhanced the differentiation of B-cells. It is a secreted factor that is highly expressed in adipocytes. Intracellularly, PBEF acts as a cytosolic enzyme involved in nicotinamide adenine dinucleotide (NAD) synthesis. PBEF levels positively correlate with obesity and type 2 diabetes mellitus and can bind the insulin receptor to lower blood sugar.
UniGene ID
Hs.489615
UniProt ID (eCommerce)
P43490
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.