human MXI1 Adenovirus
This is an Adenovirus expressing Human MXI1.
ADV-216108
Ad-h-MXI1
Ready-to-use Adenovirus expressing Human MXI1 (MAX interactor 1, dimerization protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
bHLHc11; MAD2; MXD2; MXI
Description (Vector)
Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.
Gene ID
4601
Gene Name (Vector)
MAX interactor 1, dimerization protein
Gene Symbol
MXI1
HGNC ID
HGNC:7534
ORF Size (aa)
888
ORF Size (bp)
888 bp
RefSeq ID
NM_005962
RefSeq Synonyms
NM_130439, NM_005962, NM_001008541, BC035128, BC012907,
Species
human
UniGene ID
Hs.602078
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.