human MAP3K2 Adenovirus

Name 
Ad-h-MAP3K2
Cat No 
ADV-214929
Availability
4-5 weeks
Categories
Adenovirus, Over-Expression

This is an Adenovirus expressing Human MAP3K2.

ADV-214929
Ad-h-MAP3K2

Ready-to-use Adenovirus expressing Human MAP3K2 (mitogen-activated protein kinase kinase kinase 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
CMV
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MAP/ERK kinase kinase 2; MAPK/ERK kinase kinase 2; MEK kinase 2; MEKK 2; MEKK2; MEKK2B; mitogen-activated protein kinase kinase kinase 2
Description (eCommerce)
MEKK2 is a serine-threonine kinase and activator of kinases in the MAP kinase signaling pathway. MAPKs are activated through the kinase cascade of MAPK, MAPK kinase (MAPKK), and MAPKK kinase (MAPKKK). MEK2 is also known as MAPKKK2 (mitogen-activated protein kinase kinase kinase 2). MEKK2 regulates the JNK and ERK5 activation.
Description (Vector)
MAP3K2 is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.
Gene ID
10746
Gene Name (eCommerce)
mitogen-activated protein kinase kinase kinase 2
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase 2
Gene Symbol
MAP3K2
HGNC ID
HGNC:6854
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1860
ORF Size (bp)
1860 bp
Protein Name (eCommerce)
Mitogen-activated protein kinase kinase kinase 2
RefSeq ID
NM_006609
RefSeq Synonyms
NM_006609, BC136293,
Research Areas
BDNF Signaling,EGFR Signaling,EPO Signaling,GnRH Signaling,Insulin Signaling,Interleukin Signaling,JAK-STAT Signaling,Kinase/Phosphatase,MAPK Signaling,Neurobiology,Signal Transduction,TNF Signaling,VEGF Signaling
Research Areas (Faceted)
cell_biology,immunology,neurobiology,signal_transduction
Species
human
Target Sentence
MEKK2 is a serine-threonine kinase and activator of kinases in the MAP kinase signaling pathway. MAPKs are activated through the kinase cascade of MAPK, MAPK kinase (MAPKK), and MAPKK kinase (MAPKKK). MEK2 is also known as MAPKKK2 (mitogen-activated protein kinase kinase kinase 2). MEKK2 regulates the JNK and ERK5 activation.
UniGene ID
Hs.145605
UniProt ID (eCommerce)
Q9Y2U5

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.