Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FTH1

Gene Name

ferritin heavy chain 1

Gene ID

2495

Gene Synonyms

FHC; FTH; FTHL6; HFE5; PIG15; PLIF

ORF Size

552 bp

RefSeq#

BC104643

Gene Description

FTH1 encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. FTH1 has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

UniGene ID

Hs.645560

HGNC ID

HGNC:3976