Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

ERLEC1

Gene Name

endoplasmic reticulum lectin 1

Gene ID

27248

Gene Synonyms

C2orf30; CIM; CL24936; CL25084; HEL117; XTP3-B; XTP3TPB

ORF Size

1452 bp

RefSeq#

BC013129

Gene Description

ERLEC1 encodes a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21.

UniGene ID

Hs.713845

HGNC ID

HGNC:25222