mouse TFAM Over-expression AAV

Cat. No: AAV-274078

Availability: Immediate

Name: AAV-m-TFAM

This is an AAV expressing Mouse Tfam.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tfam
Gene Name: transcription factor A, mitochondrial
Gene ID: 21780
Gene Synonyms: AI661103; Hmgts; mtTFA; tsHMG
ORF Size: 732 bp
RefSeq#: BC001987
Gene Description: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M. Associates with mitochondrial DNA.
UniGene ID: Mm.229292