mouse TFAM shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-274078
Availability:
3-5 weeks
Name:
Ad-m-TFAM-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Tfam.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Tfam
- Gene Name
- transcription factor A, mitochondrial
- Gene ID
- 21780
- Gene Synonyms
- AI661103; Hmgts; mtTFA; tsHMG
- ORF Size
- 732 bp
- RefSeq#
- NM_009360
- Gene Description
- Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind and bend DNA. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA. target DNA. Interacts with TFB1M and TFB2M. Associates with mitochondrial DNA.
- UniGene ID
- Mm.229292
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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