human MAP4K2 Over-expression AAV

Cat. No: AAV-214950

Availability: 3-5 weeks

Name: AAV-h-MAP4K2

This is an AAV expressing Human MAP4K2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MAP4K2
Gene Name: mitogen-activated protein kinase kinase kinase kinase 2
Gene ID: 5871
Gene Synonyms: BL44; GCK; RAB8IP
ORF Size: 2439 bp
RefSeq#: BC047865
Gene Description: MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
UniGene ID: Hs.534341
HGNC ID: HGNC:6864