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human MAP4K2 shRNA silencing AAV

Name 
AAV-h-MAP4K2-shRNA
Cat No 
shAAV-214950
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Human MAP4K2.

shAAV-214950
AAV-h-MAP4K2-shRNA

Ready-to-use AAV expressing shRNA for silencing of Human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BL44; GCK; RAB8IP
Description (Vector)
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
Gene ID
5871
Gene Name (Vector)
mitogen-activated protein kinase kinase kinase kinase 2
Gene Symbol
MAP4K2
HGNC ID
HGNC:6864
ORF Size (aa)
2439
ORF Size (bp)
2439 bp
RefSeq ID
NM_004579
RefSeq Synonyms
NM_004579, NM_001307990, BC047865,
Species
human
UniGene ID
Hs.534341

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.