AAV-Cre-GFP (AAV serotype 8) AAV
Cre recombinase is a Type I topoisomerase from P1 bacteriophage that catalyzes site-specific recombination of DNA between loxP sites. loxP is a 34 bp DNA sequence at which confers directionality. Cre recombinase is used as a tool to genetically modify genes, such as to delete a segment of DNA flanked by LoxP sites in cultured cells or experimental animals.
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- Viral Backbone
- Recombinant AAV
- AAV Serotype
- CMV (ubiquitous)
- Storage Buffer
- PBS/5% Glycerol
- 1x10^13 GC/ml
- Gene Symbol
- Cre Recombinase
This product is referenced in the following publications:
- Al-Onaizi M, etc (2016). Regulation of Cognitive Processing by Hippocampal Cholinergic Tone. Cerebral Cortex.
- B Kolisnyk, etc (2016). Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors. Journal of Neuroscience.
- AA Jaramillo, etc (2018). Silencing the insular-striatal circuit decreases alcohol self-administration and increases sensitivity to alcohol. Behavioural Brain Research.
- S MINABE, etc (2020). Inducible Kiss1 knockdown in the hypothalamic arcuate nucleus suppressed pulsatile secretion of luteinizing hormone in male mice. Journal of Reproduction and Development.