mouse TANK Over-expression AAV

Cat. No: AAV-273684

Availability: 3-5 weeks

Name: AAV-m-TANK

This is an AAV expressing Mouse Tank.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter: none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer: PBS/5% Glycerol

Species: Mouse
Gene Symbol: Tank
Gene Name: TRAF family member-associated Nf-kappa B activator
Gene ID: 21353
Gene Synonyms: C86182; E430026L09Rik; I-TRAF
ORF Size: 1242 bp
RefSeq#: BC026148
Gene Description: Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
UniGene ID: Mm.244393