mouse TANK shRNA silencing AAV

Name 
AAV-m-TANK-shRNA
Cat No 
shAAV-273684
Availability
4-5 weeks
Categories
AAV, shRNA-Silencing

This is an AAV expressing shRNA for silencing of Mouse Tank.

shAAV-273684
AAV-m-TANK-shRNA

Ready-to-use AAV expressing shRNA for silencing of Mouse Tank (TRAF family member-associated Nf-kappa B activator). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C86182; E430026L09Rik; I-TRAF
Description (Vector)
Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.
Gene ID
21353
Gene Name (Vector)
TRAF family member-associated Nf-kappa B activator
Gene Symbol
Tank
ORF Size (aa)
1242
ORF Size (bp)
1242 bp
RefSeq ID
NM_011529
RefSeq Synonyms
NM_011529, NM_001164072, NM_001164071, BC026148,
Species
mouse
UniGene ID
Mm.244393

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.