human ABCA4 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-200050
Availability:
3-5 weeks
Name:
Ad-h-ABCA4
This is an Adenovirus expressing Human ABCA4.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ABCA4
- Gene Name
- ATP binding cassette subfamily A member 4
- Gene ID
- 24
- Gene Synonyms
- ABC10; ABCR; ARMD2; CORD3; FFM; RMP; RP19; STGD; STGD1
- ORF Size
- 6822 bp
- RefSeq#
- BC172565
- Gene Description
- The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
- UniGene ID
- Hs.416707
- HGNC ID
- HGNC:34
Related Products
Product | Cat No. |
---|---|
Ad-h-ABCA4 | ADV-200049 |
Ad-m-ABCA4 | ADV-251762 |
AAV-h-ABCA4-shRNA | shAAV-200050 |
AAV-m-ABCA4-shRNA | shAAV-251762 |
Ad-h-ABCA4-shRNA | shADV-200050 |
Ad-m-ABCA4-shRNA | shADV-251762 |
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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