human MYOC shRNA silencing AAV

Cat. No: shAAV-216226

Availability: 6-8 weeks

Name: AAV-h-MYOC-shRNA

This is an AAV expressing shRNA for silencing of Human MYOC.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: MYOC
Gene Name: myocilin
Gene ID: 4653
Gene Synonyms: GLC1A; GPOA; JOAG; JOAG1; TIGR
ORF Size: 1515 bp
RefSeq#: NM_000261
Gene Description: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
UniGene ID: Hs.436037
HGNC ID: HGNC:7610