human MYOC Over-expression AAV

Name 
AAV-h-MYOC
Cat No 
AAV-216226
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MYOC.

AAV-216226
AAV-h-MYOC

Ready-to-use AAV expressing Human MYOC (myocilin). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GLC1A; GPOA; JOAG; JOAG1; TIGR
Description (Vector)
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Gene ID
4653
Gene Name (Vector)
myocilin
Gene Symbol
MYOC
HGNC ID
HGNC:7610
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_000261
RefSeq Synonyms
NM_000261, BC029261,
Species
human
UniGene ID
Hs.436037

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.