human MYOC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MYOC.
shADV-216226
Ad-h-MYOC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MYOC (myocilin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GLC1A; GPOA; JOAG; JOAG1; TIGR
Description (Vector)
MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Gene ID
4653
Gene Name (Vector)
myocilin
Gene Symbol
MYOC
HGNC ID
HGNC:7610
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_000261
RefSeq Synonyms
NM_000261, BC029261,
Species
human
UniGene ID
Hs.436037
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.

