Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

GBA3

Gene Name

glucosylceramidase beta 3 (gene/pseudogene)

Gene ID

57733

Gene Synonyms

CBG; CBGL1; GLUC; KLRP

ORF Size

1410 bp

RefSeq#

BC101829

Gene Description

GBA3, or cytosolic beta-glucosidase (EC 3.2.1.21), is a predominantly liver enzyme that efficiently hydrolyzes beta-D-glucoside and beta-D-galactoside, but not any known physiologic beta-glycoside, suggesting that it may be involved in detoxification of plant glycosides (de Graaf et al., 2001 (PubMed 11389701)). GBA3 also has significant neutral glycosylceramidase activity (EC 3.2.1.62), suggesting that it may be involved in a nonlysosomal catabolic pathway of glucosylceramide metabolism (Hayashi et al., 2007 (PubMed 17595169)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.653107

HGNC ID

HGNC:19069