Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

IGSF8

Gene Name

immunoglobulin superfamily member 8

Gene ID

93185

Gene Synonyms

CD316; CD81P3; EWI-2; EWI2; KCT-4; LIR-D1; PGRL

ORF Size

1842 bp

RefSeq#

BC053881

Gene Description

IGSF8 encodes a member the EWI subfamily of the immunoglobulin protein superfamily. Members of this family contain a single transmembrane domain, an EWI (Glu-Trp-Ile)-motif and a variable number of immunoglobulin domains. This protein interacts with the tetraspanins CD81 and CD9 and may regulate their role in certain cellular functions including cell migration and viral infection. The encoded protein may also function as a tumor suppressor by inhibiting the proliferation of certain cancers. Alternate splicing results in multiple transcript variants that encode the same protein.

UniGene ID

Hs.332012

HGNC ID

HGNC:17813