Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Rhou

Gene Name

ras homolog family member U

Gene ID

69581

Gene Synonyms

2310026M05Rik; AI182090; Arhu; CDC42L1; G28K; mG28K; WRCH-1; WRCH1

ORF Size

783 bp

RefSeq#

BC156318

Gene Description

Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.

UniGene ID

Mm.168257