Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SULF2

Gene Name

sulfatase 2

Gene ID

55959

Gene Synonyms

HSULF-2

ORF Size

2613 bp

RefSeq#

BC110539

Gene Description

Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 (PubMed 16192265)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.162016

HGNC ID

HGNC:20392