Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

SPP1

Gene Name

secreted phosphoprotein 1

Gene ID

6696

Gene Synonyms

BNSP; BSPI; ETA-1; OPN

ORF Size

864 bp

RefSeq#

BC093033

Gene Description

SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.

UniGene ID

Hs.313

HGNC ID

HGNC:11255