Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

TERF2

Gene Name

telomeric repeat binding factor 2

Gene ID

7014

Gene Synonyms

TRBF2; TRF2

ORF Size

756 bp

RefSeq#

BC024890

Gene Description

TERF2 encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

UniGene ID

Hs.63335

HGNC ID

HGNC:11729