human ASAH1 Adenovirus
Category: Adenovirus > Over-Expression
Cat. No: ADV-201505
Availability:
Immediate
Name:
Ad-h-ASAH1
This is an Adenovirus expressing Human ASAH1.
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Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- CMV
- Reporter
- none, optional GFP, CFP, YFP, RFP or mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- ASAH1
- Gene Name
- N-acylsphingosine amidohydrolase 1
- Gene ID
- 427
- Gene Synonyms
- AC; ACDase; ASAH; PHP; PHP32; SMAPME
- ORF Size
- 1188 bp
- RefSeq#
- BC016481
- Gene Description
- ASAH1 encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene.
- UniGene ID
- Hs.633993
- HGNC ID
- HGNC:735
Product Citations
This product is referenced in the following publications:
- JL Roh, JY Park, EH Kim, HJ Jang (2016). Targeting acid ceramidase sensitises head and neck cancer to cisplatin. European Journal of Cance.
- MM Azuma, etc (2017). Endogenous acid ceramidase protects epithelial cells from Porphyromonas gingivalis-induced inflammation in vitro. Biochemical and Biophysical Research Communications.
Related Products
Control Products
Product | Cat No. |
---|---|
Ad-CMV-Luc | 1000 |
Ad-GFP | 1060 |
Ad-CMV-b-Gal | 1080 |
Ad-Null | 1240 |
Ad-CMV-Null | 1300 |
Ad-RFP | 1660 |
Ad-CFP | 1766 |
Ad-mCherry | 1767 |
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