Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

COASY

Gene Name

Coenzyme A synthase

Gene ID

80347

Gene Synonyms

DPCK; NBIA6; NBP; pOV-2; PPAT; UKR1

ORF Size

1695 bp

RefSeq#

BC067254

Gene Description

Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. COASY is a bifunctional enzyme that catalyzes the 2 last steps in CoA synthesis. These activities are performed by 2 separate enzymes, phosphopantetheine adenylyltransferase (PPAT; EC 2.7.7.3) and dephospho-CoA kinase (DPCK; EC 2.7.1.24), in prokaryotes (Daugherty et al., 2002 (PubMed 11923312)).(supplied by OMIM, Mar 2008)

UniGene ID

Hs.709231

HGNC ID

HGNC:29932