Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

EIF2B1

Gene Name

eukaryotic translation initiation factor 2B subunit alpha

Gene ID

1967

Gene Synonyms

EIF2B; EIF2BA

ORF Size

918 bp

RefSeq#

BC104188

Gene Description

EIF2B1 encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.

UniGene ID

Hs.716475

HGNC ID

HGNC:3257