Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

CMV

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Human

Gene Symbol

FLVCR2

Gene Name

feline leukemia virus subgroup C cellular receptor family member 2

Gene ID

55640

Gene Synonyms

C14orf58; CCT; EPV; FLVCRL14q; MFSD7C; PVHH

ORF Size

1581 bp

RefSeq#

BC019087

Gene Description

FLVCR2 encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.

UniGene ID

Hs.615289

HGNC ID

HGNC:20105