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von Hippel-Lindau tumor suppressor


Product Name: Ad-VHL

Product Category: human Adenovirus Type5 (dE1/E3)

Gene Name: VHL

Gene Alias: VHL, RCA1, VHL1, HRCA1

GeneBank Number: BC058831

Description:

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen.

Titer: 1x1010 PFU/ml *

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Cat. No. Tag Promoter Species Price **
1613 CMV human $445.00

  • * titer may vary depends on batch
  • ** Price for US/Canada customers only, please inquire about international pricing.
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