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Deoxyribonuclease I adenovirus


Product Name: Ad-DNASE I

Product Category: Ready-use human Adenovirus Type5 (dE1/E3)

Gene Name: DNASE I

Gene Alias: Dnase I, DNL1, DNASE1, DNASE-1

GeneBank Number: BC029437

Description:

This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity.

Titer: 1x1010 PFU/ml

Volume: 200ul

Storage Buffer: DMEM with 2% BSA & 2.5% Glycerol

Availability: In stock, same day shipping available for orders placed before 1PM.

Catalog No. Tag Promoter Species Price **
1612 CMV human $690.00

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